Nov 22, 2019   1:02 p.m. Cecília
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Course syllabus 426B2_4B - Biochemistry I (FCFT - SS 2018/2019)


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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code: 426B2_4B
Course unit title: Biochemistry I
Mode of completion and Number of ECTS credits: Exam (4 credits)
Course contents:
1.Biochemistry - basic course (allowance 2/2)
 
a.In this course following topics will be taught:
Chemical composition of living organisms. Ions, trace elements, occurrence and function, role of water. Buffers. Energetics of living organisms. Equilibrium and noni-equilibrium processes. Chemical equilibria. Coupling of endergonic and exergonic reactions. High-energy bond.
b.DNA, structure, properties. DNA denaturation. Replication. Types, structures and functions of RNAs. Transcription. Genetic code. Enzymatic activity of RNA.
Amino acids, structure, properties, chemical reactions. Peptide bond. Proteins and polypeptides, their properties and structure. Methods of protein structure study. Proteosynthesis.
c.Monosaccharides. Stereochemistry. Biologically important monosaccharides, their derivatives, oligosaccharides and polysaccharides. Glycoside bond.
Fatty acids, triacylglycerols, waxes, sterols, complex lipids.
d.Enzymes. Enzymic reaction, kinetics, inhibition.
Cell metabolism and its regulation. Concept of operon by Jacob and Monod. Regulation by changes of enzymic activities.
e.Anaerobic and aerobic catabolism of glucose. Gluconeogenesis. Citric acid cycle. Anaplerotic reactions. Glyoxylate cycle. Pentose cycle.
f.Oxidative phosphorylation. Respiratory chain. Coupling of substrate oxidation and ATP synthesis. Protonmotive force. Transport of reducing equivalents, substrates and products of phosphorylarion.
Utilization of fatty acids. Enzymologic, energetic, transport, and regulatory aspects. Biosynthesis of fatty acids.
Photosynthetic phosphorylation and carbon fixation. Dark-reactions of photosynthesis. Fixation of CO2 in C3 and C4 plants. Photorespiration. Calvin cycle.


Last modification made by Ing. Tomáš Molnár on 08/16/2018.

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