Course syllabus 426B2_4B - Biochemistry I (FCFT - SS 2018/2019)
Information sheet ECTS Syllabus
Last modification made by Ing. Tomáš Molnár on 08/16/2018.
|University: ||Slovak University of Technology in Bratislava|
|Faculty: ||Faculty of Chemical and Food Technology|
|Course unit code: ||426B2_4B|
|Course unit title: ||Biochemistry I|
|Mode of completion and Number of ECTS credits: ||Exam (4 credits)|
|Course contents: |
|1.||Biochemistry - basic course (allowance 2/2)|
|a.||In this course following topics will be taught:|
Chemical composition of living organisms. Ions, trace elements, occurrence and function, role of water. Buffers. Energetics of living organisms. Equilibrium and noni-equilibrium processes. Chemical equilibria. Coupling of endergonic and exergonic reactions. High-energy bond.
|b.||DNA, structure, properties. DNA denaturation. Replication. Types, structures and functions of RNAs. Transcription. Genetic code. Enzymatic activity of RNA.|
Amino acids, structure, properties, chemical reactions. Peptide bond. Proteins and polypeptides, their properties and structure. Methods of protein structure study. Proteosynthesis.
|c.||Monosaccharides. Stereochemistry. Biologically important monosaccharides, their derivatives, oligosaccharides and polysaccharides. Glycoside bond.|
Fatty acids, triacylglycerols, waxes, sterols, complex lipids.
|d.||Enzymes. Enzymic reaction, kinetics, inhibition.|
Cell metabolism and its regulation. Concept of operon by Jacob and Monod. Regulation by changes of enzymic activities.
|e.||Anaerobic and aerobic catabolism of glucose. Gluconeogenesis. Citric acid cycle. Anaplerotic reactions. Glyoxylate cycle. Pentose cycle.|
|f.||Oxidative phosphorylation. Respiratory chain. Coupling of substrate oxidation and ATP synthesis. Protonmotive force. Transport of reducing equivalents, substrates and products of phosphorylarion.|
Utilization of fatty acids. Enzymologic, energetic, transport, and regulatory aspects. Biosynthesis of fatty acids.
Photosynthetic phosphorylation and carbon fixation. Dark-reactions of photosynthesis. Fixation of CO2 in C3 and C4 plants. Photorespiration. Calvin cycle.