Oct 21, 2019   0:43 a.m. Uršuľa
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Course syllabus N426B0_4I - Biochemistry (FCFT - WS 2019/2020)

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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit title: Biochemistry
Course unit code: N426B0_4I
Mode of completion and Number of ECTS credits: Exam (4 credits)
Name of lecturer: prof. Ing. Albert Breier, DrSc. (person responsible for course)
doc. Ing. Boris Lakatoš, PhD. (examiner, instructor, lecturer) - slovak, english
Learning outcomes of the course unit:
The goal of this course is to teach students basics of intermediary metabolism, i.e. metabolism of nitrogen compounds (amino acids, nucleotides, lipids, etc.), structure and properties of biological membranes, membrane phenomena, and biochemical bases of important physiological processes.
Prerequisites and co-requisites: none
Course contents:
The goal of this course is to teach students basics of intermediary metabolism. Following topics will be taught:
Utilization and detoxification of ammonia in ureogenetic cycle. General reactions of amino acids. Biosynthesis of encoded amino acids. Reactions of transfer of C1 groups. Degradation of amino acid side chains. Glucogenic and ketogenic amino acids. Biosynthetic pathways associated with degradation of amino acids.
Biosynthesis and degradation of purine and pyrimidine bases and nucleotides. Biosynthesis of deoxyribonucleotides. Haem biosynthesis and degradation. Pterine biosynthesis.
Metabolism of complex lipids, icosanoids, izoprenoids, steroids, carotenoids, polyketides. Primary and secondary metabolism.
Biological membranes, composition, structure, models, biogenesis.
Energetics and transport mechanisms.
Biological signalizations. Reception, transduction, receptors, transduction mechanisms. Second messenger. Effector mechanisms. Hormons.
Integrative mechanisms in cells and organisms (homeostasis, pH, Ca, glucose). Blood coagulation. Nerve system and its function.
Light and living organisms. Light as energy source. Response of organisms to the light pulse. Bioluminiscence. Mechanism of vision.
Biochemical basis of motility and contractility. Cytoskeleton. Muscles and other contractile proteins.
Metabolism of xenobiotics. The role of oxygen in metabolism. Reactive oxygen species and their detoxification. Enzymic requirements of detoxification
Recommended or required reading:
ŠKÁRKA, B. -- NOVÁK, M. -- FERENČÍK, M. Biochémia. Bratislava: Slovak Academic Press , 2000.
VOET, J G. -- VOET, D. Biochemistry. New York: John Wiley & Sons, 1995. 1361 p. ISBN 0-471-58651-X.

Planned learning activities and teaching methods: There will be 12-13 lectures during the semester. Individual discussions about the topics of lectures are possible.
Assesment methods and criteria: No monitoring of student's progress during the course is proposed.
Language of instruction: Slovak, English
Work placement(s): There is no compulsory work placement in the course unit.

Last modification made by Ing. Tomáš Molnár on 09/23/2019.

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