Informačný list ECTS Sylabus
Sylabus predmetu 414C0_4B - Drug chemistry (FCFT - WS 2020/2021)
|University:||Slovak University of Technology in Bratislava|
|Faculty:||Faculty of Chemical and Food Technology|
|Course unit code:||414C0_4B|
|Course unit title:||Drug chemistry|
|Mode of delivery, planned learning activities and teaching methods:|
|Recommended semester/trimester:||-- item not defined --|
|Level of study:||1.|
|Prerequisites for registration:||none|
|Elaboration of semestral work on: The Selected drug - properties, mechanism of action, methods of synthesis, analogous derivatives.|
The exam consists of a written test and an oral test for 50 points. To successfully passing the exam, the student must achieve at least 28 points.
Students are grated as follows: A 46-50 points, B 41-45 points, C 37-40 points, D 32-36 points, E 28-31 points.
|Learning outcomes of the course unit:|
|Subject is based on the knowledge of organic chemistry and biochemistry and gives basic information on the relationship between drug and its receptor at molecular level. It explains the strategic principles of drug development. In the interpretation are discussed selected categories of active substances in terms of their structural similarity, and mechanism of their action on molecular level.|
|Brief syllabus: mechanism of drug action, enzyme inhibitors, receptor theory, agonist, antagonist.
Developmental stages of drug synthesis, lead structure, synthesis of analogs, synthetic strategies.
Total anesthetics, analgesics, morphine analogs.
Antipyretics, non-steroidal anti-inflammatory drugs.
Peripheral nervous system drugs, cholinergic system, local anesthetics, muscle relaxants.
Adrenergics, adrenolytic agents, ergot alkaloids.
Antihistamines, H1 and H2 developments of antihistamines.
Antibacterials - sulfonamides, antibiotics - penicillins and cephalosporins.
Disinfectants, antiseptics and antifungals.
Vitamins A, E, respectively. C and Group B.
|Recommended or required reading:|
|Language of instruction:||slovak or english|
|The course is recommended for students in the third year of study in the program Nutrition and cosmetics|
|Assessed students in total: 356|
|Name of lecturer(s):||doc. Ing. Dušan Berkeš, CSc. (person responsible for course) - slovak, english|
|Last modification:||20. 5. 2019|
|Supervisor:||doc. Ing. Dušan Berkeš, CSc. and programme supervisor|
Last modification made by Ing. Tomáš Molnár on 05/20/2019.