May 22, 2019   1:12 p.m. Júlia, Juliana
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Course syllabus N423U0_4B - Introduction to Bioprocesses (FCFT - SS 2017/2018)

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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code: N423U0_4B
Course unit title: Introduction to Bioprocesses
Mode of delivery, planned learning activities and teaching methods:
lecture2 hours weekly (on-site method)
laboratory/construction practice2 hours weekly (on-site method)

Credits allocated: 4
Recommended semester/trimester: Automation, Information Engineering and Management in Chemistry and Food Industry - bachelor (compulsory), 4. semester
Automation, Information Engineering and Management in Chemistry and Food Industry - bachelor (compulsory), 4. semester
Chemical Engineering - bachelor (compulsory), 4. semester
Level of study: 1.
Prerequisites for registration: none
Assesment methods:
Students write two written tests from problems for 50 points in total. To pass them, minimum 27.5 points are needed. A written exam from the theory is classified by 50 points. A minimum needed is 27.5 points. A student will receive credits if both parts are passed successfully. Exam grades are as follows: A 91-100 points, B 82-90 points, C 73-81 point, D 64-72 points, E 55-63 points.
Learning outcomes of the course unit:
Students obtain knowledge about the cell structure and properties in relation to their performance in the environment of biotechnological processes and about basic stoichiometric calculations and determination of kinetic parameters.
Course contents:
1. Microbiology
 cell structure, eukaryots, prokaryots
 groups of microorganisms – bacteria, yeasts, mycellial fungi, algae, animal and plant cells
 aerobes and anaerobes
 cell nutrition, composition of cultivation media, life cycle

2. Biochemistry
 basic biochemical compounds – lipids, saccharides, DNA and RNA, amino acids and proteins. Structure and function in living organisms.

3. Principle biotechnological production processes
 Brief of overview of biotechnological production processes. Amino acids. Enzymes. Antibiotics. Ethanol. Organic acids. Polysaccharides. Vitamins. Specialty chemicals.

4. Metabolic stoichiometry and energetics
 Principles of production and consumption of energy inside the cells (ADP and ATP), form of carbon catabolism, respiration chain, biosynthesis of small molecules and macromolecules, cell membrane transport and principle regulatory mechanisms. Application of this knowledge on the production processes of final metabolites
 Stechiometry of cell growth and product formation, yield coefficients
 Thermodynamics of cell cultivations

5. Laboratory exercises
 Determination of enzyme kinetics using the initial rate method
 Determination of kinetic parameters of Michaelis-Menten equation using the progress curve method
Recommended or required reading:
ŠKÁRKA, B. Biochémia. Bratislava: Alfa, 1999.
HUDECOVÁ, D. -- MAJTÁN, V. Mikrobiológia I. Bratislava: Vydavateľstvo STU v Bratislave, 2002. 189 p. ISBN 80-227-1663-4.
BÁLEŠ, V. -- MÉSZÁROS, A. -- POLAKOVIČ, M. -- ŠTEFUCA, V. -- MUNTEAN, O. Biochemické technológie: Biochemical Technologies. Bratislava : AB-ART, 2003. 128 p. ISBN 80-89006-75-2.
DORAN, P M. Bioprocess Engineering Principles. London : Academic Press, 1995. 439 p. ISBN 0-12-220856-0.

Language of instruction: slovak or english
The course is compulsory for the students of the study program Chemical Engineering
Courses evaluation:
Assessed students in total: 262

5,3 %13,4 %22,9 %33,6 %18,7 %6,1 %
Name of lecturer(s): Ing. Monika Antošová, PhD. (examiner, instructor, tutor) - slovak, english
Ing. Viera Illeová, PhD. (examiner, instructor, lecturer, tutor) - slovak, english
prof. Ing. Milan Polakovič, CSc. (person responsible for course) - slovak, english
Last modification: 22. 9. 2017
Supervisor: prof. Ing. Milan Polakovič, CSc. and programme supervisor

Last modification made by Ing. Tomáš Molnár on 09/22/2017.

Type of output: