Information sheet ECTS Syllabus
Course syllabus N400G0_4D - Genomics, Proteomics and Their Applications (FCFT - 2018/2019 - post-graduate studies)
|University:||Slovak University of Technology in Bratislava|
|Faculty:||Faculty of Chemical and Food Technology|
|Course unit code:||N400G0_4D|
|Course unit title:||Genomics, Proteomics and Their Applications|
|Mode of delivery, planned learning activities and teaching methods:|
|Recommended semester/trimester:||Biochemistry - doctoral (semi-compulsory), 2. year|
Biochemistry - doctoral (semi-compulsory), 2. year
|Level of study:||3.|
|Prerequisites for registration:||none|
|The conditions for passing the course are in accordance with the Study Rules of the STU in Bratislava.|
|Learning outcomes of the course unit:|
|Subject the Genomics, Proteomics and their Applications deals with a rapidly evolving scientific area that introduces students into genomes, proteomes and databases that store various data about genes, proteins, genomes and proteomes. Students would learn about genomics, proteomics and bioinformatics and offer basic knowledge of genome sequencing, major differences between prokaryotic and eukaryotic genomes, basic proteomics and its applications. Students woul gain knowledge of comparative, evolutionary, human genomics and functional genomics. The acquired knowledge during the course would be helpful to those students who continue postgraduate studies.|
|1. Classification of genomics. Sequencing of genomes and sequencing methods („next-generation sequencing“). General/main databases of genomes.
2. Structure, organization and composition of prokaryotic genomes. Microbial genomics and genome epidemiology.
3. Function genomics, metagenomics and methods of metagenomics.
4. Evolution and structure of mitochondrial genomes, mtDNA and mitochondrial diseases.
5. Structure, organization and composition of eukaryotic genomes. Repetitive a transponable genetic elements and their effect on genome. Telomeric and subtelomeric regions.
6. DNA methylations, RNAi and silencing of genes expresion.
7. History of human genome sequencing. Evolution of human genome and structure variations (STR, VNTR, SNP).
8. Genomics of human diseases, nutritional genomics, epigenomics and methods of epigenomics.
9. Malditof and ESI, their use in proteomics, spectra and their analysis.
10. Tandem mass spectrometry, peptide sequencing by means of tandem mass spectrometry.
11. Affinity purification of proteins and TAP tag.
|Recommended or required reading:|
|Language of instruction:||-- item not defined --|
|Assessed students in total: 3|
|Name of lecturer(s):||doc. Ing. Boris Lakatoš, PhD. (person responsible for course) - slovak|
|Last modification:||27. 8. 2018|
|Supervisor:||doc. Ing. Boris Lakatoš, PhD. and programme supervisor|
Last modification made by Ing. Tomáš Molnár on 08/27/2018.