Oct 18, 2019   0:50 a.m. Lukáš
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Course syllabus N426B3_4I - Bioenergetics of Cells and Organisms (FCFT - WS 2019/2020)


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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code: N426B3_4I
Course unit title: Bioenergetics of Cells and Organisms
Mode of delivery, planned learning activities and teaching methods:
lecture2 hours weekly (on-site method)
seminar2 hours weekly (on-site method)

 
Credits allocated: 5
 
Recommended semester/trimester: Biochemistry and Biomedical Technologies - master (compulsory), 3. semester
Level of study: 2.
Prerequisites for registration: none
 
Assesment methods:
Students have to successfully pass the oral exam to complete the course. Requirement of the completion of the course is active participation in the seminars and passing in the final written exam. The final written exam consists of a two parts, theory and calculation exercise, it is required to obtain at least 56% of both parts.
 
Learning outcomes of the course unit:
Students obtain knowledge about biochemical processes that cells use for energy conversion and synthesis ATP, needed to maintain cellular functions. They understand differences in energy metabolism of cells (animals, plants, microorganisms), which differ in energy source, path of carbon assimilation, and terminal electron acceptor.
 
Course contents:
- Thermodynamic aspects of biological processes.
- Catabolic pathways and synthesis of reduced equivalents in chemotrophs
- Mitochondria and their functions in energetic metabolism. Respiration chain.
- Coupling of proton-motive force and ATP synthesis. Mitchell's chemiosmotic theory of oxidative phosphorylation.
- Light as the source of energy. Phototrophs. Conversion of light energy to chemical energy.
- Photosystems, electron transport and ATP synthesis during photosynthesis.
- Cyclic and noncyclic phosphorylation. Anoxygenic photosynthesis. Dark phase of photosynthesis.
- Neurons, action potential and neurotransmission.
- Mechanisms and energetics of solute transport across membranes.
- Contractility and motility of biological systems.
- Bacteria and Archaea, properties of their energy metabolism depending on energy source, path of carbon assimilation, and terminal electron acceptor.
- Unique energy metabolic pathways serve for ATP formation and energy transformation in microorganisms.
- Hydrogenases; their catalytic activity, structure and function. Task of hydrogenases in bioenergetics of microorganisms.
 
Recommended or required reading:
Basic:
VOET, D. -- VOET, J G. Biochemistry. New York : John Wiley & Sons, 1995. 1361 p. ISBN 0-471-58651-X.
STRYER, L. Biochemistry. New York : W.H.Freeman, 1988. 1089 p. ISBN 0-7167-1920-7.
HUDECOVÁ, D. -- ŠIMKOVIČ, M. Mikrobiológia. In.
SKULAČEV, V P. Bioenergetika.Membrannyje preobrazovateli energii. Moskva : Vyšča škola, 1989. 270 p.

 
Language of instruction: slovak or english
 
Notes:
 
Courses evaluation:
Assessed students in total: 63

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50,8 %39,7 %7,9 %1,6 %0 %0 %
Name of lecturer(s): prof. Ing. Albert Breier, DrSc. (examiner, instructor, lecturer) - slovak, english
doc. Ing. Martin Šimkovič, PhD. (person responsible for course) - slovak, english
 
Last modification: 29. 1. 2019
Supervisor: doc. Ing. Martin Šimkovič, PhD. and programme supervisor


Last modification made by Ing. Tomáš Molnár on 01/29/2019.

Type of output: