17. 10. 2019  7:24 Hedviga
Akademický informační systém

Sylabus předmětu N426B0_4I - Biochemistry (FCFT - WS 2019/2020)

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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code: N426B0_4I
Course unit title: Biochemistry
Mode of delivery, planned learning activities and teaching methods:
lecture2 hours weekly (on-site method)
seminar1 hour weekly (on-site method)

Credits allocated: 4
Recommended semester/trimester: Biochemistry and Biomedical Technologies - master (compulsory), 1. semester
Biochemistry and Biomedical Technologies - master (compulsory), 1. semester
Biotechnology - master (compulsory), 1. semester
Biotechnology - master (compulsory), 1. semester
Level of study: 2.
Prerequisites for registration: none
Assesment methods:
An indispensable condition to close the course is to pass the examen with a note better than FX.
Learning outcomes of the course unit:
The goal of this course is to teach students basics of intermediary metabolism, i.e. metabolism of nitrogen compounds (amino acids, nucleotides, lipids, etc.), structure and properties of biological membranes, membrane phenomena, and biochemical bases of important physiological processes.
Course contents:
The goal of this course is to teach students basics of intermediary metabolism. Following topics will be taught:
Utilization and detoxification of ammonia in ureogenetic cycle. General reactions of amino acids. Biosynthesis of encoded amino acids. Reactions of transfer of C1 groups. Degradation of amino acid side chains. Glucogenic and ketogenic amino acids. Biosynthetic pathways associated with degradation of amino acids.
Biosynthesis and degradation of purine and pyrimidine bases and nucleotides. Biosynthesis of deoxyribonucleotides. Haem biosynthesis and degradation. Pterine biosynthesis.
Metabolism of complex lipids, icosanoids, izoprenoids, steroids, carotenoids, polyketides. Primary and secondary metabolism.
Biological membranes, composition, structure, models, biogenesis.
Energetics and transport mechanisms.
Biological signalizations. Reception, transduction, receptors, transduction mechanisms. Second messenger. Effector mechanisms. Hormons.
Integrative mechanisms in cells and organisms (homeostasis, pH, Ca, glucose). Blood coagulation. Nerve system and its function.
Light and living organisms. Light as energy source. Response of organisms to the light pulse. Bioluminiscence. Mechanism of vision.
Biochemical basis of motility and contractility. Cytoskeleton. Muscles and other contractile proteins.
Metabolism of xenobiotics. The role of oxygen in metabolism. Reactive oxygen species and their detoxification. Enzymic requirements of detoxification
Recommended or required reading:
ŠKÁRKA, B. -- NOVÁK, M. -- FERENČÍK, M. Biochémia. Bratislava: Slovak Academic Press , 2000.
VOET, J G. -- VOET, D. Biochemistry. New York: John Wiley & Sons, 1995. 1361 p. ISBN 0-471-58651-X.

Language of instruction: slovak or english
Courses evaluation:
Assessed students in total: 209

19,6 %23,4 %20,6 %21,5 %12,9 %2,0 %
Name of lecturer(s): prof. Ing. Albert Breier, DrSc. (person responsible for course)
doc. Ing. Boris Lakatoš, PhD. (examiner, instructor, lecturer) - slovak, english
Last modification: 23. 9. 2019
Supervisor: prof. Ing. Albert Breier, DrSc. and programme supervisor

Last modification made by Ing. Tomáš Molnár on 09/23/2019.

Typ výstupu: