Oct 28, 2020   5:16 a.m. Dobromila
Academic information system

Course syllabus N426B0_4I - Biochemistry (FCFT - SS 2019/2020)

     Information sheet          ECTS          Syllabus          

     Slovak          English          

University: Slovak University of Technology in Bratislava
Faculty of Chemical and Food Technology
Course unit code:
Course unit title:
Mode of delivery, planned learning activities and teaching methods:
2 hours weekly (on-site method)
1 hour weekly (on-site method)

Credits allocated:
Recommended semester/trimester:
-- item not defined --
Level of study:
Prerequisites for registration:
Assesment methods:
An indispensable condition to close the course is to pass the examen with a note better than FX.
Learning outcomes of the course unit:
The goal of this course is to teach students basics of intermediary metabolism, i.e. metabolism of nitrogen compounds (amino acids, nucleotides, lipids, etc.), structure and properties of biological membranes, membrane phenomena, and biochemical bases of important physiological processes.
Course contents:
The goal of this course is to teach students basics of intermediary metabolism. Following topics will be taught:
Utilization and detoxification of ammonia in ureogenetic cycle. General reactions of amino acids. Biosynthesis of encoded amino acids. Reactions of transfer of C1 groups. Degradation of amino acid side chains. Glucogenic and ketogenic amino acids. Biosynthetic pathways associated with degradation of amino acids.
Biosynthesis and degradation of purine and pyrimidine bases and nucleotides. Biosynthesis of deoxyribonucleotides. Haem biosynthesis and degradation. Pterine biosynthesis.
Metabolism of complex lipids, icosanoids, izoprenoids, steroids, carotenoids, polyketides. Primary and secondary metabolism.
Biological membranes, composition, structure, models, biogenesis.
Energetics and transport mechanisms.
Biological signalizations. Reception, transduction, receptors, transduction mechanisms. Second messenger. Effector mechanisms. Hormons.
Integrative mechanisms in cells and organisms (homeostasis, pH, Ca, glucose). Blood coagulation. Nerve system and its function.
Light and living organisms. Light as energy source. Response of organisms to the light pulse. Bioluminiscence. Mechanism of vision.
Biochemical basis of motility and contractility. Cytoskeleton. Muscles and other contractile proteins.
Metabolism of xenobiotics. The role of oxygen in metabolism. Reactive oxygen species and their detoxification. Enzymic requirements of detoxification
Recommended or required reading:
ŠKÁRKA, B. -- NOVÁK, M. -- FERENČÍK, M. Biochémia. Bratislava: Slovak Academic Press , 2000.
VOET, J G. -- VOET, D. Biochemistry. New York: John Wiley & Sons, 1995. 1361 p. ISBN 0-471-58651-X.

Language of instruction:
slovak or english
Courses evaluation:
Assessed students in total: 257

19,5 %
28,8 %
18,7 %
19,8 %
11,7 %
1,5 %
Name of lecturer(s):
prof. Ing. Albert Breier, DrSc. (person responsible for course)
Last modification:
17. 7. 2019
prof. Ing. Albert Breier, DrSc. and programme supervisor

Last modification made by Ing. Tomáš Molnár on 07/17/2019.

Type of output: