Oct 28, 2020   4:24 a.m. Dobromila
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Course syllabus N426Z1_4B - Fundamentals of Biochemistry (FCFT - SS 2019/2020)

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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code:
Course unit title:
Fundamentals of Biochemistry
Mode of delivery, planned learning activities and teaching methods:
3 hours weekly (on-site method)

Credits allocated:
Recommended semester/trimester:
Biotechnology - bachelor (compulsory), 4. semester
Food, Nutrition, Cosmetics - bachelor (compulsory), 4. semester
Chemistry, Medical Chemistry and Chemical Materials - bachelor (compulsory), 6. semester
Level of study: 1.
Prerequisites for registration: none
Assesment methods:
Students must pass examen with the note better than E according to the standard scale.
Learning outcomes of the course unit:
The course provides information about cell constituents, structure and function of biopolymers, enzymes and the basics of energetic metabolism.
Course contents:
Chemical composition of living organisms. Ions, trace elements, occurrence and function, role of water. Buffers. Energetics of living organisms. Equilibrium and noni-equilibrium processes. Chemical equilibria. Coupling of endergonic and exergonic reactions. High-energy bond.
DNA, structure, properties. DNA denaturation. Replication. Types, structures and functions of RNAs. Transcription. Genetic code. Enzymatic activity of RNA.
Amino acids, structure, properties, chemical reactions. Peptide bond. Proteins and polypeptides, their properties and structure. Methods of protein structure study. Proteosynthesis.
Monosaccharides. Stereochemistry. Biologically important monosaccharides, their derivatives, oligosaccharides and polysaccharides. Glycoside bond.
Fatty acids, triacylglycerols, waxes, sterols, complex lipids.
Enzymes. Enzymic reaction, kinetics, inhibition.
Cell metabolism and its regulation. Concept of operon by Jacob and Monod. Regulation by changes of enzymic activities.
Anaerobic and aerobic catabolism of glucose. Gluconeogenesis. Citric acid cycle. Anaplerotic reactions. Glyoxylate cycle. Pentose cycle. Oxidative phosphorylation. Respiratory chain. Coupling of substrate oxidation and ATP synthesis. Protonmotive force. Transport of reducing equivalents, substrates and products of phosphorylarion.
Utilization of fatty acids. Enzymologic, energetic, transport, and regulatory aspects.
Photosynthetic phosphorylation and carbon fixation. Dark-reactions of photosynthesis. Fixation of CO2 in C3 and C4 plants. Photorespiration. Calvin cycle.

Recommended or required reading:
ŠKÁRKA, B. -- NOVÁK, M. -- FERENČÍK, M. Biochémia. Bratislava: Slovak Academic Press , 2000.
VOET, D. -- VOET, J G. Biochemistry. New York : John Wiley & Sons, 1995. 1361 p. ISBN 0-471-58651-X.
STRYER, L. Biochemistry. New York : W.H.Freeman, 1988. 1089 p. ISBN 0-7167-1920-7.
HOLDE, K. -- MATHEWS, C K. Biochemistry. Redwood City : The Benjamin/Cummings Publ.Comp, 1990. 1129 p. ISBN 0-8053-5015-2.

Language of instruction:
slovak or english
Courses evaluation:
Assessed students in total: 842

4,0 %
10,9 %
25,1 %29,6 %
28,7 %
1,7 %
Name of lecturer(s):
doc. Ing. Boris Lakatoš, PhD. (person responsible for course)
Last modification: 17. 7. 2019
doc. Ing. Boris Lakatoš, PhD. and programme supervisor

Last modification made by Ing. Tomáš Molnár on 07/17/2019.

Type of output: