Oct 21, 2019   11:17 p.m. Uršuľa
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Course syllabus N400B4_4D - Advanced Biophysical Chemistry (FCFT - 2019/2020 - post-graduate studies)


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University: Slovak University of Technology in Bratislava
Faculty: Faculty of Chemical and Food Technology
Course unit code: N400B4_4D
Course unit title: Advanced Biophysical Chemistry
Mode of delivery, planned learning activities and teaching methods:
lecture2 hours weekly (on-site method)

 
Credits allocated: 3
 
Recommended semester/trimester: Chemical Engineering - doctoral (optional), 1. year
Chemical Physics - doctoral (optional), 1. year
Macromolecular Chemistry - doctoral (optional), 1. year
Macromolecular Chemistry - doctoral (optional), 1. year
Organic Technology and Technology of Fuels - doctoral (optional), 1. year
Physical Chemistry - doctoral (optional), 1. year
Theoretical and Computational Chemistry - doctoral (optional), 1. year
Level of study: 3.
Prerequisites for registration: none
 
Assesment methods:
Test - maxuimum 60 points. Presentation - maximum 40 points.
To pass the exam, students are required to obtain: A - minimum 85 points. B - minimum 75 points, C- minimum 65 points. D- minimum 60 points. E- minimum 56 points.
 
Learning outcomes of the course unit:
The aim of this subject is to obtain a basic knowledge about the structure of proteins and DNA as well as about their thermodynamic and kinetic properties and mutual interactions. Student will understand the basic principles of NMR and X-ray in the structural elucidation of biomolecules. Students will understand the structural aspects of biomembranes and transport phenomena. Basic principles of non-equilibrium thermodynamics in biodisciplines. Students will understand the role of redox-active metals and radicals in the damage to biomolecules as well as protective mechanisms against deleterious effects of free radicals. Students will become familiar with quantum-chemical calculations of electronic structure of biomolecules.
 
Course contents:
Structure of proteins and DNA - experimental methods of their structural studies. Biological membranes and trasnport thorugh membranes. Diffusion - mathematical account. Non-equilibrium description of transport phenomena. Free radicals and antioxidants in biosystems. Use of magnetic resonance and quantum-chemical calculations in the study of biomolecules.
 
Recommended or required reading:
Basic:
ALLEN, J. Biophysical Chemistry. Chichester, UK: Wiley-Blackwell, 2008. 492 p. ISBN 978-1-4051-2436-2.
KODÍČEK, M. -- KARPENKO, V. Biofysikální chemie. Praha : Academia, 2000. 337 p. ISBN 80-200-0791-1.
KARPENKO, V. -- KODÍČEK , M. Biofysikální chemie. Praha: Praha: Academia, 2000. 250 p. ISBN 80-200-0791-1.

 
Language of instruction: slovak or english
 
Notes:
The subject is recommended for the 2nd year of doctoral study.
 
Courses evaluation:
Assessed students in total: 16

PN
100,0 %0 %
Name of lecturer(s): prof. Ing. Marián Valko, DrSc. (person responsible for course) - slovak, english
 
Last modification: 26. 4. 2019
Supervisor: prof. Ing. Marián Valko, DrSc. and programme supervisor


Last modification made by Ing. Tomáš Molnár on 04/26/2019.

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