Information sheet ECTS Syllabus
Course syllabus 414C2_4I - Drug chemistry (FCFT - WS 2020/2021)
|University:||Slovak University of Technology in Bratislava|
|Faculty:||Faculty of Chemical and Food Technology|
|Course unit code:||414C2_4I|
|Course unit title:||Drug chemistry|
|Mode of delivery, planned learning activities and teaching methods:|
|Recommended semester/trimester:||Biochemistry and Biomedical Technologies - master (semi-compulsory), 1. semester|
|Level of study:||2.|
|Prerequisites for registration:||none|
|Elaboration of semestral work on: The Selected drug - properties, mechanism of action, methods of synthesis, analogous derivatives.|
The exam consists of a written test and an oral test for 50 points. To successfully passing the exam, the student must achieve at least 28 points.
Students are grated as follows: A 46-50 points, B 41-45 points, C 37-40 points, D 32-36 points, E 28-31 points.
|Learning outcomes of the course unit:|
|This course builds on the knowledge of organic chemistry and biochemistry and gives basic information on the relationship between drug and receptor at the molecular level. It explains the strategic principles that apply to drug development. In the lectures are discussed selected categories of active substances in terms of their structural similarity, respectively. mechanism of action at the molecular level.|
|Mechanism of drug action, enzyme inhibitors, receptor theory, agonist, antagonist.
Drug design, development and synthesis, lead structure, synthesis of analogs, synthetic strategies.
Total anesthetics, analgesics, opioid analgetics.
Antipyretics, non-steroidal anti-inflammatory drugs.
Peripheral nervous system drugs, cholinergic system, local anesthetics, muscle relaxants.
Adrenergics, adrenolytic, ergot alkaloids.
Antihistamines, development of H1 and H2 (antiulcer agents) antihistamines.
Antibacterials - sulfonamides, antibiotics - penicillins and cephalosporins.
Disinfectants, antiseptics and antifungals.
|Recommended or required reading:|
|Language of instruction:||slovak or english|
|The course is recommended for students in the first year of the enginiering study in the program Biotebology and food technology|
|Assessed students in total: 130|
|Name of lecturer(s):||doc. Ing. Dušan Berkeš, CSc. (person responsible for course) - slovak, english|
|Last modification:||20. 5. 2019|
|Supervisor:||doc. Ing. Dušan Berkeš, CSc. and programme supervisor|
Last modification made by Ing. Tomáš Molnár on 05/20/2019.