Dec 14, 2019   4:09 a.m. Branislava, Bronislava
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Ing. Pavol Jakubec, PhD.
Identification number: 4023
University e-mail: pavol.jakubec [at] stuba.sk
 
Odborný asistent CSc.,PhD. - Department of Organic Chemistry (IOCP FCFT)
 
External colleague - Faculty of Chemical and Food Technology (STU)

Contacts     Lesson     Final thesis     Projects     Publications     Supervised theses     

Basic information

Basic information about a final thesis

Type of thesis: Bachelor thesis
Thesis title:Crystallisation-induced asymmetric transformation of diastereomeric salts of α-aminoacids
Written by (author): Bc. Natália Farkašová
Department: Department of Organic Chemistry (IOCP FCFT)
Thesis supervisor: Ing. Pavol Jakubec, PhD.
Opponent:Ing. Martin Markovič, PhD.
Final thesis progress:Final thesis was successfully defended.


Additional information

Additional information about the final thesis follows. Click on the language link to display the information in the desired language.

Language of final thesis:Slovak

Slovak        English

Title of the thesis:Kryštalizáciou-indukovaná asymetrická transformácia diastereomérnych solí α-aminokyselín
Summary:Bakalárska práca sa zameriava na kryštalizáciou-indukovanú asymetrickú transformáciu diastereomérnych solí α-aminokyselín. Teoretická časť je zameraná na štúdium prípravy enantiomérne čistých γ-substituovaných α-amino-γ-oxobutánových kyselín aza-Michaelovou adíciou a využitie Weinrebovho amidu v syntéze komplexných molekúl. V experimentálnej časti je zahrnutá príprava racemických γ-substituovaných α-amino-γ-oxobutánových kyselín. Pojednáva sa v nej tiež o hľadaní vhodných podmienok pre kryštalizáciou-indukovanú asymetrickú transformáciu diastereomérnych solí a aplikáciu metódy CIAT v príprave enantiomérne čistých γ-substituovaných α-amino-γ-oxobutánových kyselín.
Key words:Diastereomérne soli, CIAT, α-amino-γ-oxobutánová kyselina, aza-Michaelová adícia, Weinrebov amid

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