Feb 21, 2020   11:33 a.m. Eleonóra
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doc. Ing. Peter Šafař, CSc.
Identification number: 3367
University e-mail: peter.safar [at] stuba.sk
Docent CSc.,PhD. - Department of Organic Chemistry (IOCP FCFT)

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Basic information

Basic information about a final thesis

Type of thesis: Diploma thesis
Thesis title:Preparation and Reactions of Benzoquinazolinedione
Written by (author): Ing. Barbora Balónová
Department: Department of Organic Chemistry (IOCP FCFT)
Thesis supervisor: doc. Ing. Peter Šafař, CSc.
Opponent:doc. Ing. Ján Světlík, DrSc.
Final thesis progress:Final thesis was successfully defended.

Additional information

Additional information about the final thesis follows. Click on the language link to display the information in the desired language.

Language of final thesis:Slovak

Slovak        English

Title of the thesis:Preparation and Reactions of Benzoquinazolinedione
Summary:Phenantroquinolizidine alkaloids are classified as substances with a broad range of biological activity. This diploma thesis consists of literature review about preparation of N-substituted piperidine-2-carboxylic acids, which belong to appropriate starting materials for mentioned alkaloids preparation. The diploma thesis deals with information, which have been obtained during synthesis of the chiral carboxylic acid. The cyclization of this acid leads to preparation of benzoquinazolinedione, which is the key synthon for synthesis of enantiomeric pure non-natural cryptopleurine's alkaloids.
Key words:cryptopleurine, quinolizinedione, cyclization, chirality

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Final thesis (final thesis appendices) unlimited
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