Sep 20, 2019   7:13 a.m. Ľuboslav, Ľuboslava
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Ing. Peter Šafař, CSc.
Identification number: 3367
University e-mail: peter.safar [at]
Odborný asistent CSc.,PhD. - Department of Organic Chemistry (IOCP FCFT)

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Basic information

Basic information about a final thesis

Type of thesis: Bachelor thesis
Thesis title:Preparation and rections of the (S)-N-benzyl-6-oxopipecolinic acid
Written by (author): Ing. Barbora Balónová
Department: Department of Organic Chemistry (IOCP FCFT)
Thesis supervisor: Ing. Peter Šafař, CSc.
Final thesis progress:Final thesis was successfully defended.

Additional information

Additional information about the final thesis follows. Click on the language link to display the information in the desired language.

Language of final thesis:Slovak

Slovak        English

Title of the thesis:Preparation and rections of the (S)-N-benzyl-6-oxopipecolinic acid
Summary:The aim of my work was to develop literature search concerning the preparation od N-substitued piperidine carboxylic acid, then prepare (S)-N-benzyl-6-oxopiperidine-2-carboxylic acid and try to make its cyclization in the last step of the synthesis under different conditions to form chinazolidindione. The basic information, which were obtained in the synthesis of the chiraly (S)-N-benzyl-6-oxopiperidine-2-carboxylic acid, are summarized in this work. The (S)-N-benzyl-6-oxopiperidín-2-carboxyl acid has managed to be prepared by method, which was developed in our laboratory, and the enantiomeric clear L-2-aminoadipic acid has been used as a starting material.
Key words:cyclization, chirality, (S)-N-benzyl-6-oxopiperidine-2-carboxylic acid

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