Oct 18, 2019   0:34 a.m. Lukáš
Academic information system

Summary of topics offered - Institute of Biotechnology (FCFT)

Basic information

Type of work: Dissertation thesis
Topic: Manánolytické acetylesterázy
Title of topic in English: Mannanolytic acetyl esterases
State of topic: approved (Dr.h.c. prof. Ing. Ján Šajbidor, DrSc. - Chairperson of Departmental Board)
Thesis supervisor: Mgr. Vladimír Puchart, PhD.
Faculty: Faculty of Chemical and Food Technology
Supervising department: Institute of Biotechnology - FCFT
Max. no. of students: --
Academic year:2019/2020
Proposed by: Mgr. Vladimír Puchart, PhD.
External educational institution: Institute of Chemistry of the Slovak Academy of Sciences
Annotation: Galaktoglukomanán je najrozšírenejšou hemicelulózou mäkkých drevín a druhou najrozšírenejšou hemicelulózou tvrdých drevín. K heterogenite tohto polysacharidu prispieva aj acetylácia jeho hlavného reťazca, ktorá výrazne sťažuje jeho enzýmovú depolymerizáciu. Napriek týmto poznatkom sa o acetylmanánesterázach nevie takmer vôbec nič, lebo izolovaných ich bolo len niekoľko a ani tie, ktoré boli izolované, neboli hlbšie charakterizované. Táto téma nepochybne prinesie úplne nové poznatky, ktoré určite prispejú nielen k lepšej charakterizácii ostatných manánolytických enzýmov, ale aj k ich širšiemu praktickému využitiu.
Annotation in English: Galactoglucomannan is the most abundant softwood hemicellulose and the second most abundant hemicellulose of hardwoods. Its heterogeneity is also increased by its main chain acetylation which significantly hampers its enzymatic depolymerization. Despite this knowledge almost nothing is known about acetylmannan esterases due to that only a few of them have been isolated and those having been isolated were not analyzed in a more detail. No doubt that this topic will afford novel findings thus not only contributing to a better characterization of other mannanolytic enzymes but also to their broader industrial application.

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D-BIOT Biotechnology