Oct 20, 2019   7:31 p.m. Vendelín
Academic information system

Summary of topics offered - Faculty of Chemical and Food Technology


Basic information

Type of work: Dissertation thesis
Topic: Charakterizácia vybraných biomakromolekúl pomocou elektrochemických metód
Title of topic in English: Characterization of the selected biomacromolecules by electrochemical methods
State of topic: approved (prof. Ing. Ján Híveš, PhD. - Chairperson of Departmental Board)
Thesis supervisor: doc. RNDr. Miroslav Gál, PhD.
Faculty: Faculty of Chemical and Food Technology
Supervising department: Department of Inorganic Technology - IICTM FCFT
Max. no. of students: --
Academic year:2019/2020
Proposed by: doc. RNDr. Miroslav Gál, PhD.
Annotation: Elektrochemické metódy spolu so spektroskopickými umožňujú štúdium niektorých biochemických vlastností vysokomolekulárnych látok (proteínov, DNA, RNA), ich vzájomných interakcií in vitro a/alebo in vivo ako aj ich interakcií s terapeuticky dôležitými nízkomolekulárnymi látkami, eventuálne detekciu pomocou biosenzorov. Dizertačná práca bude preto okrem iného zameraná na štúdium základných biochemických charakteristík biomakromolekúl a ich vzájomných interakcií a eventuálne prípravu biosenzora. Využité budú elektrochemické, spektrálne, separačné (HPLC), optické a mikroskopické (AFM) metódy. Určitá časť dizertačnej práce bude realizovaná v spolupráci s Ústavem fyzikální chemie J. Heyrovského Akademie věd ČR v Prahe resp. s Biofyzikálním ústavem AV ČR v Brne.
Annotation in English: Electrochemical methods as well as spectroscopic methods are found to be very powerful for biological/biochemical applications. Electrochemical methods have proven to be of great utility in such studies because they provide sensitive measurements and can be combined with other approaches that facilitate the protein–protein, protein D(R)NA, and high molecular compounds low molecular compounds interactions and, moreover, biosensor production. Therefore, the main goal of PhD thesis will be to study basic biochemical properties of selected biomacromolecules using electrochemical, spectroscopic, and microscopic (AFM microscopy) methods, HPLC, and their detection by biosensors. The part of this dissertation will be realized in cooperation with J. Heyrovsky Institute of Physical Chemistry AS CR, Prague, Czech Republic and Institute of Biophysics AS CR, Brno, Czech Republic.



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Programme
D-ATEM Inorganic Technologies and Materials