Nov 19, 2019   11:31 p.m. Alžbeta
Academic information system

Summary of topics offered - Faculty of Chemical and Food Technology


Basic information

Type of work: Diploma thesis
Topic: Amidy beta-substituovanej pyroglutámovej kyseliny - syntéza a biologická aktivita
Title of topic in English: Amides of beta-Substituted Pyroglutamic Acids - Synthesis and Biological Activity
State of topic: approved (prof. Ing. Anton Gatial, DrSc. - Study programme supervisor)
Thesis supervisor: doc. Ing. Dušan Berkeš, CSc.
Faculty: Faculty of Chemical and Food Technology
Supervising department: Department of Organic Chemistry - IOCP FCFT
Max. no. of students: 1
Academic year:2019/2020
Proposed by: doc. Ing. Dušan Berkeš, CSc.
Summary: Literárna rešerš - Agonisti a antagonisti P2X7 receptora so zameraním na deriváty pyroglutámovej kyseliny. Metódy stereoselektívnej syntézy substituovaných pyroglutámových kyselín a ich derivátov. Príprava východiskových enantiomérne čistých beta-aroyl pyroglutámových kyselín. Štúdium ich stereoselektívnych transformácií na ceste k cieľovým antagonistom. Identifikácia pripravených zlúčenín dostupnými fyz.- chem. metódami.



Limitations of the topic

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Restrictions by study
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ProgrammeTrack
I-TCHEM Technical ChemistryI-TCHEM-OCH organická chémia

Limit to courses
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