Nov 14, 2019   4:47 a.m. Irma
Academic information system

Summary of topics offered - Faculty of Chemical and Food Technology


Basic information

Type of work: Bachelor thesis
Topic: Vplyv valproátu na viabilitu buniek a morfológiu mitochondrií
Title of topic in English: The effect of valproate on cell viability and mitochondrial morphology
State of topic: approved (doc. Ing. Daniela Šmogrovičová, PhD. - Study programme supervisor)
Thesis supervisor: Mgr. Mária Balážová-Šimočková, PhD.
Faculty: Faculty of Chemical and Food Technology
Supervising department: Institute of Biochemistry and Microbiology - FCFT
Max. no. of students: 1
Academic year:2019/2020
Proposed by: Mgr. Mária Balážová-Šimočková, PhD.
Summary: Valproát je liečivo používané na liečbu bipolárnej poruchy. Znižuje hladinu vnútrobunkového inozitolu, hlavného regulátoru biosyntézy fosfolipidov. Pokles inozitolu zvyšuje aktivitu kľúčového enzýmu v biosyntéze kardiolipínu, čo môže mať terapeutický efekt na abnormálne mitochondrie. Cieľom projektu je využiť valproát na zlepšenie funkcie mitochondrií u pacientov s poškodeniou biosyntézou kardiolipínu.



Limitations of the topic

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Restrictions by study
The table shows restrictions by study to which the student has to be enrolled in order to sign up for the given topic.

Programme
B-BIOT Biotechnology

Limit to courses
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DepartmentCourse title
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