Dec 11, 2019   8:52 a.m. Hilda
Academic information system

Summary of topics offered - Faculty of Chemical and Food Technology


Basic information

Type of work: Bachelor thesis
Topic: Porovnanie látkami indukovanej autofágie a apoptózy v leukemických bunkách
Title of topic in English: Comparison of substance-induced autophagy and apoptosis in leukemic cells
State of topic: approved (doc. Ing. Daniela Šmogrovičová, PhD. - Study programme supervisor)
Thesis supervisor: Ing. Katarína Elefantová, PhD.
Faculty: Faculty of Chemical and Food Technology
Supervising department: Institute of Biochemistry and Microbiology - FCFT
Max. no. of students: 1
Academic year:2019/2020
Proposed by: Ing. Katarína Elefantová, PhD.
Summary: Autofágia je evolučne konzervovaný intracelulárny degradačný proces udržujúci homeostázu v bunke. Nejedná sa o priamy proces smrti bunky, ale o tzv. bunkový samokanibalizmus, pretože touto cestou si bunka degraduje vlastné proteíny, prípadne organely, a teda je schopná prežiť aj počas hladovania. Apoptóza je kontrolovaný, energeticky závislý typ bunkovej smrti a môže postihnúť samostatné bunky alebo aj ich zhluky. V tejto práci sa zameriame na sledovanie indukcie týchto dvoch typov bunkovej smrti vyvolanej cytotoxickými látkami na myšiu leukemickú líniu L1210 s alebo bez expresie P-glykoproteínu.



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Restrictions by study
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Programme
B-BIOT Biotechnology

Limit to courses
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