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Asymmetric synthesis based on a template for crystallization-induced asymmetric transformation (CIAT).

Supervisor: prof. Ing. Ľubor Fišera, DrSc.


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Project description:Submitted project is based on asymmetric synthesis of a broad scale of various syn-γ-hydroxy-α-amino acids and their consequent utilization in aimed synthesis. The crutial step is represented by aza-Michael addition in conditions of crystallization-induced asymmetric transformation (CIAT), employing β-acylacrylic template. Emphasis is put on study and optimization of conditions for CIAT with the aim of general applicability.
Kind of project:APVV ()
Department:Department of Organic Chemistry (IOCP FCFT)
Project identification:LPP-0238-06
Project status:Successfully completed
Project start date :01. 12. 2006
Project close date:30. 11. 2009
Number of workers in the project:1
Number of official workers in the project:0