May 23, 2019   11:25 a.m. Želmíra
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EMBRYOMICS: Reconstructing in space and time the cell lineage tree

Supervisor: prof. RNDr. Karol Mikula, DrSc.

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Project description:The aim of Embryomics is the morphodynamical ?reconstruction? of the cell lineage tree underlying the processes of animal embryogenesis. The goal will be achieved by developing a set of strategies, methods and algorithms to reconstruct the dynamics of cell divisions and movements from time-lapse series of high-resolution optical sections obtained by multiphoton laser scanning microscopy throughout embryonic development. Additionally to reconstruction of cell population dynamics, such kind of data is highly relevant also in investigation of early steps of cancerogenesis and drug effects in vivo. This highly interdisciplinary project forms the foundation of a new scientific field that we call Embryomics with a reference to Genomics.
Kind of project:New and Emerging Science and Technology (NEST) ()
Department:Department of Mathematics and Constructive Geometry (FCE)
Project identification:012916-2
Project status:Successfully completed
Project start date :01. 11. 2005
Project close date:31. 05. 2009
Number of workers in the project:2
Number of official workers in the project:0